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KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic  Vulnerability in Lung Cancer
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

Full article: Epigenetic modification in chromatin machinery and its  deregulation in pediatric brain tumors: Insight into epigenetic therapies
Full article: Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies

Synthesis and biological evaluation of benzomorpholine derivatives as novel  EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink
Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink

Synthesis and biological evaluation of benzomorpholine derivatives as novel  EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink
Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink

Transcriptional Regulation and Its Misregulation in Disease: Cell
Transcriptional Regulation and Its Misregulation in Disease: Cell

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

CENTER FOR CANCER RESEARCH
CENTER FOR CANCER RESEARCH

berry (@berry46566269) / Twitter
berry (@berry46566269) / Twitter

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

Luke B. Hesson · Antonia L. Pritchard Editors
Luke B. Hesson · Antonia L. Pritchard Editors

Histone methylation modifiers in medical therapeutics - ScienceDirect
Histone methylation modifiers in medical therapeutics - ScienceDirect

Vulnerabilities of Mutant SWI/SNF Complexes in Cancer: Cancer Cell
Vulnerabilities of Mutant SWI/SNF Complexes in Cancer: Cancer Cell

KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic  Vulnerability in Lung Cancer - ScienceDirect
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer - ScienceDirect

Histone methylation modifiers in medical therapeutics - ScienceDirect
Histone methylation modifiers in medical therapeutics - ScienceDirect

Synthesis and biological evaluation of benzomorpholine derivatives as novel  EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink
Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink

Role of somatic cancer mutations in human protein lysine methyltransferases  - ScienceDirect
Role of somatic cancer mutations in human protein lysine methyltransferases - ScienceDirect

Design, synthesis and biological evaluation of novel  1-methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinolins as potential EZH2  inhibitors - RSC Advances (RSC Publishing) DOI:10.1039/C5RA02365C
Design, synthesis and biological evaluation of novel 1-methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinolins as potential EZH2 inhibitors - RSC Advances (RSC Publishing) DOI:10.1039/C5RA02365C

High-throughput screening with nucleosome substrate identifies  small-molecule inhibitors of the human histone lysine methyltransferase  NSD2 - Journal of Biological Chemistry
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2 - Journal of Biological Chemistry

Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling  in KMT2D Mutant Melanoma - ScienceDirect
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma - ScienceDirect

An Alternative Approach to ChIP-Seq Normalization Enables Detection of  Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2  Inhibition | PLOS ONE
An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition | PLOS ONE

IJMS | Free Full-Text | Epigenetic Control of a Local Chromatin Landscape
IJMS | Free Full-Text | Epigenetic Control of a Local Chromatin Landscape